Research Grant Program 2019-03-09T17:28:21+00:00

Research Grant Program

The Cure RTD Foundation (CureRTD) and its international affiliates announce the availability of funding for basic science and clinical research on the natural history, biochemical basis, and treatment of Riboflavin Transporter Deficiency (RTD).  We encourage investigators at all professional levels to submit their best ideas. There are no geographical limitations to this funding.

Download Information

Please carefully review CureRTD’s Grant Program General Policies and General Requirements for Applications at the links below prior to completing the Grant Application form. 

      Grant Application Process and Requirements (PDF)
      Research Grant Policies (PDF)
      Application Form (Word)

Budget and Award Size

Awards range from $10,000 to $100,000 per year. Strong preference is given to excellent, early-career and early-stage proposals in the range of $30,000 to $50,000 per year. Smaller and larger awards will be considered. Grants are usually for one year, with the possibility of renewal for up to two additional years, subject to satisfactory progress reports. We expect successful projects to be able to attract future funding from other organizations.

Letter of Intent

A letter of intent is mandatory for all grant applications and can be submitted at any time to The letter of intent is a one-page document describing the applicant’s research plan/idea in applying for funding.  Based on the outcome of this review, the applicant may be invited to submit a full application. 

Grant Application Deadline

The deadline for submission of the completed research grant application is October 31 and May 31 each yearCureRTD will notify applicants as to whether or not their project will be funded, usually within a few months of the submission deadline. We anticipate awarding several grants each year.

Types of Proposals Sought

We are interested in providing “seed grant funding” to young investigators as well as attracting experienced investigators new to the field of RTD basic science or clinical research. We anticipate that these funds will be used for the testing of initial hypotheses and the collection of preliminary data leading to successful long-term funding by the National Institutes of Health (NIH) and other major granting institutions around the world.

CureRTD allows young, non-tenured investigators to include in their submitted budget up to 75% of the total grant amount as PI salary. In addition, for those clinical applications where volunteers must travel to a clinical research site, these travel expenses will be handled separately and will be excluded from the budget maximums mentioned above. 

Grant Program Priorities

The goal of CureRTD´s Research Grant Program is to advance medical knowledge of the basic mechanism of the disease.  Although CureRTD will consider any research proposal related to RTD, it is particularly interested in supporting research that will have an impact on therapeutic approaches including the following areas:

  • Understanding pathophysiological mechanism of neurodegeneration in RTD and implications for therapies.
  • Flavin transport in RTD and strategies for optimizing flavin delivery in patients.
  • Genetic, epigenetic and protein approaches that target improved riboflavin transporter functionality.
  • Discovery and validation of biomarkers in RTD.
  • The search for compounds that may improve mitochondrial/cellular performance and/or provide neuroprotection in RTD.

Applications for any of these areas will be accepted for grants, and will be given preferential consideration in the CureRTD Research Grant Program cycle.

Contact Information

Keith Massey
Science Director
Cure RTD Foundation, Inc.
Local Line:  403-244-4549